Sprionolactone plus Hydrochlorothiazide (Aldactazide)
Veterinary & Aquatic Services Department, Drs. Foster & Smith

Spironolactone and hydrochlorothiazide are diuretics used to remove excess fluid from the body. The combination is used to treat congestive heart failure and ascites (fluid in the abdomen). The combination is often used when the pet does not respond to other diuretics. Side effects or signs of overdose or toxicity may include dehydration with excessive thirst and decreased urine production, or electrolyte imbalances, possibly with weakness, lethargy, restlessness, stumbling, dizziness, muscle pain or cramping, or lack of energy. May cause vomiting and diarrhea in some animals. If you see any of these signs, contact your veterinarian immediately. Your pet needs to eat and drink well while taking spironolactone and hydrochlorothiazide or the risk of side effects increases. Do not use in pregnant or lactating animals (female animals nursing their young), or in animals who are not producing urine, those with Cushing's disease (hyperadrenocorticism) who are taking the medication mitotane, or in animals with Addison's disease (hypoadrenocorticism). Use with extreme caution in animals with severe kidney or liver disease, electrolyte disturbances, water imbalances, high uric acid levels, gout, lupus (SLE), or diabetes mellitus.
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Keep this and all other medications out of the reach of children and pets.

If you think your pet has been poisoned...

Contact your veterinarian or one of the Animal Poison Hotlines (listed below) if you think your pet may have accidentally received or been given an overdose of the medication.

**ASPCA Animal Poison Control Center - 24-hour service available throughout North America.

1-888-4ANI-HELP (1-888-426-4435). $65.00 per case, billed to caller's credit card.

Follow-up calls can be made for no additional charge by dialing 888-299-2973.

There is no charge when the call involves a product covered by the Animal Product Safety Service.

**Pet Poison Helpline - 24-hour service available throughout North America for pet owners and veterinary professionals who require assistance with treating a potentially poisoned pet.

1-800-213-6680 ($59.00 per incident). Staffed 24-hours a day.

Updated 6/20/17

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