Trimethoprim/Sulfa (Bactrim™, Septra, Tribrissen®)
Veterinary & Aquatic Services Department, Drs. Foster & Smith

Trimethoprim, an antibiotic, is often used in combination with a sulfa drug, such as sulfamethoxazole or sulfadiazine. The combination is used to treat susceptible bacterial and protozoal infections in dogs, cats, and other pets. n dogs, keratoconjunctivitis sicca (KCS, dry eye) may rarely occur with long-term use of trimethoprim/sulfa. Stop giving the medication and consult your veterinarian if your pet experiences discharge from the eye, redness of the eye, squinting, or other signs related to the eye. In long-term therapy, your veterinarian may request periodic exams to monitor tear production. Also contact your veterinarian if your pet experiences pale gums, bleeding tendencies, fever, depression, loss of appetite, vomiting, diarrhea, sore joints, lameness, skin rashes, increased thirst or urination, skin rashes with possible sensitivity to sunlight.

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Keep this and all other medications out of the reach of children and pets.

If you think your pet has been poisoned...

Contact your veterinarian or one of the Animal Poison Hotlines (listed below) if you think your pet may have accidentally received or been given an overdose of the medication.

**ASPCA Animal Poison Control Center - 24-hour service available throughout North America.

1-888-4ANI-HELP (1-888-426-4435). $65.00 per case, billed to caller's credit card.

Follow-up calls can be made for no additional charge by dialing 888-299-2973.

There is no charge when the call involves a product covered by the Animal Product Safety Service.

**Pet Poison Helpline - 24-hour service available throughout North America for pet owners and veterinary professionals who require assistance with treating a potentially poisoned pet.

1-800-213-6680 ($59.00 per incident). Staffed 24-hours a day.

Updated 6/20/17

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