Sodium Phosphate Enema Toxicity in Dogs and Cats
Veterinary & Aquatic Services Department, Drs. Foster & Smith

Sodium Phosphate Enemas.

Fleet enemas.

General Information
Excessive amounts of sodium and phosphate contained in these enemas are absorbed in the colon causing an increase of sodium and phosphate in the blood. This causes changes in the other blood electrolytes which results in further symptoms.

Toxic Dose
Over 25 pounds of body weight - 4 fl. oz.
Less than 25 pounds of body weight - 2 fl. oz.

Signs usually occur within 30-60 minutes after administration of the enema, and include lethargy, ataxia, heart rhythm abnormalities, muscle tremors, and seizures. Less common are bloody diarrhea and vomiting.

Immediate Action
Induce vomiting. Seek veterinary attention.

Veterinary Care
General treatment: If exposure was by ingestion, the induction of vomiting may be continued, gastric lavage is performed, and activated charcoal is administered.

Supportive treatment: The sodium, phosphorus, potassium, calcium, glucose, BUN, and bicarbonate levels are measured in the blood and appropriate IV fluids are given. Calcium gluconate may need to be given intravenously, while an EKG is performed to monitor for side effects. Fluids should be given cautiously while monitoring for symptoms of cerebral edema.

Specific treatment: Unavailable.



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Updated 6/20/17

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