Bio Spot-Spot On for Dogs, K-9 Advantix
Type of Drug
Form and Storage
Topical oil (spot-on)
Store at room temperature.
Indications for Use
Treatment and prevention of flea and tick infestations.
EPA approved for use in dogs. Available over the counter. Permethrin is a manmade form of the naturally occurring pyrethrin. (Permethrins should NOT be used on cats.) Both interfere with the nervous system of the flea or tick paralyzing and killing it. May take 3-7 days for highest effect.
The topical spot-ons spread over the body with the body oils, and collect in the hair follicles and then are released over time (up to 1 month) from the hair follicles onto the skin and hair.
Usual Dose and Administration
Apply according to manufacturer's recommendations. The product must be placed on the skin for it to be effective.
May see skin irritation including redness, itchiness, rash, hair discoloration or hair loss at site of application. May see lethargy or drooling. Consult your veterinarian and bathe the dog.
Do not use on patients hypersensitive (allergic) to it.
Do not use on cats, or on dogs which a cat may groom.
Do not use on sick or debilitated dogs.
Consult your veterinarian before using on dogs with heart, liver, or kidney disease.
Do not allow product to contaminate the environment as it is toxic to aquatic life.
Consult your veterinarian before using on pregnant or nursing dogs.
Do not use with other flea/tick control products that are put on the pet (sprays, collars, other spot-on oils) unless directed by your veterinarian.
May see drooling, vomiting, diarrhea, incoordination, increased excitability, seizures, or change in body temperature (higher or lower).