Pet Education Dogs
Pet Education Dogs Pet Education Dogs Pet Education Dogs

Learn about Vetco
Dog Food Cat Food New Brands - Healthy Choices Just Added!
Free Shipping on orders over $49
Video Center
Drugs That May Or May Not Be Used in Pregnant Dogs
Veterinary & Aquatic Services Department, Drs. Foster & Smith
Reproduction and Breeding
Print Article | Email Article
Bookmark and Share
Click here for a pdf version of this article.  See related products at Pet Supplies

With a few exceptions as noted below, one should avoid using all medications in pregnant and lactating (nursing) dogs. There may be instances in which a medication not recommended for use during pregnancy may need to be used to save the life of the bitch, even though it may potentially harm the fetuses. Always consult with your veterinarian before administering any drug or supplement to a pregnant or nursing dog.

NOTE: This is only a partial listing of drugs that should be avoided in pregnant or nursing dogs. A listing of all such drugs is beyond the scope of this article. If you have concerns regarding a specific drug, type it in the search box above.

Drug May Be Used Do Not Use Safety Studies in Dogs Not Available; Consult Your Veterinarian
Acemannan   x  
Acepromazine   x  
Acetylcysteine Use as an antidote, only.    
Activated Charcoal x    
Albuterol   x  
Allopurinol   x  
Amikacin   x  
Aminopenicillins (Amoxicillin, Ampicillin)     x
Aminopentamide (Centrine)     x
Amitraz (Mitaban, Preventic Collars)   x  
Amitriptyline (Elavil)   x  
Antacids (Maalox, Milk of Magnesia)   x  
Artificial Tears x    
Aspirin   x  
Atropine Eye Medication x    
Azathioprine (Imuran)   x  
Bismuth Subsalicylate (Pepto Bismol)   x  
Buspirone (Buspar)   x  
Butorphanol (Torbutrol, Torbugesic)   x  
Carprofen (Rimadyl)   x  
Cephalosporins (Keflex, Cefa-drops)     x
Chlorpheniramine (Chlor-Trimeton)   x  
Cimetidine (Tagamet)   x  
Cisapride (Propulsid)   x  
Clemastine (Tavist 1)   x  
Clindamycin (Antirobe)     Use with caution.
Clomipramine (Clomicalm, Anafranil)   x  
Cyclosporin (Optimmune)     x
Cyproheptadine   x  
Dextromethorphan   x  
Diazepam (Valium)   x  
Digoxin (Cardoxin)     Give only if clearly needed.
Dimenhydrinate (Dramamine)   x  
Diphenhydramine (Benadryl)   x  
DMSO (Synotic)   x  
DOCP   x  
Enalapril (Enacard, Vasotec)   x  
Enrofloxacin (Baytril)   x  
Epsiprantel (Cestex)   x  
Erythromycin   x  
Erythropoietin (EPO, Epogen)   x  
Estrogens (ECP, DES)   x  
Etodolac (EtoGesic)   x  
Extended Spectrum Penicillins (Carbenicillin)   x  
Famotidine (Pepcid)   x  
Fatty acids     Not recommended for pregnant humans.
Fenbendazole (Panacur) x    
Fentanyl   x  
Fipronil (Frontline)
  Frontline Plus
  Frontline Top Spot
  Frontline Spray
Fludrocortisone (Florinef)   x  
Fluoxetine (Prozac)   x  
Furosemide (Lasix)   x  
Gentamicin (Gentocin)   x  
Glucocorticosteroids (Prednisone, Dexamethasone, Hydrocortisone)   x  
Glycosaminoglycans (Glucosamine, Chondroitin)     x
Griseofulvin (Fulvicin)   x  
Hydroxyzine (Atarax)   x  
Imidacloprid (Advantage)   x  
Insulin x   Note: Diabetic dogs should not be bred.
Itraconazole (Sporanox)   x  
Ivermectin (Heartgard) x    
Kanamycin (Amforal, Kantrim)   x  
Kaolin (Kaopectate, Canine Pectate)
**See Note Below
Loperamide (Immodium)   x  
Lufenuron (Program) x    
Mannitol   x  
Marbofloxacin (Zeniquin)   x  
Mebendazole (Telmintic)   x  
Meclofenamic Acid (Arquel)   x  
Melarsomine (Immiticide)   x  
Methimazole (Tapazole)   x  
Methionine (Methigel, Methio-Form)   x  
Metoclopramide (Reglan)     x
Metronidazole (Flagyl)   x  
Mibolerone (Cheque Drops)   x  
Milbemycin (Interceptor, Sentinel) x    
Misoprostol (Cytotec)   x  
Mitotane (o,p-DDD, Lysodren)   x  
Natural Penicillins (Penicillin G, Crystiben, Penicillin V)   x  
Neomycin   x  
Novobiocin (Albaplex)   x  
Omeprazole (Prilosec)   x  
Orbifloxacin (Orbax)   x  
Oxytocin (Pitocin) At delivery.    
Pancreatic Enzymes (Pancrezyme, Viokase-K) x    
Penicillinase Resistant Penicillins (Cloxacillin)   x  
Pentobarbital   x  
Permethrin (Bio Spot-Spot On for Dogs, K9 Advantix)     x
Phenobarbital   x  
Phenylbutazone   x  
Phenylpropanolamine (Dexatrim)   x  
Phenytoin (Dilantin)   x  
Phytonadione (Vitamin K)   x  
Piperazine (Happy Jack Kennel Wormer, Purina Liquid Wormer, Sergeants Worm Away, Pipa Tabs, Piper Worm Wormer) Other wormers are preferred.    
Polysulfated Glycosaminoglycan (Adequan)   x  
Potassium Depends on type & reason for use.    
Potassium Bromide   x  
Potentiated Penicillins (Clavamox, Augmentin)   x  
Primidone   x  
Psyllium (Metamucil, Vetasyl) x    
Pyrantel Pamoate (ProWormer-2, Nemex) Do not use wormers with additional ingredients.    
Ranitidine (Zantac)   x  
Rotenone (Goodwinol Ointment) x   Caution: Do not use on puppies, or expose puppies to this medication.
Selamectin (Revolution) x    
Selegiline (Anipryl)   x  
Sucralfate     x
Sulfadimethoxine (Albon, Bactrovet)   x  
Sulfadimethoxine & Ormetroprim (Primor)   x  
Terbutaline   x  
Tetracyclines (Doxycycline, Oxytetracycline)   x  
Theophylline (Theo-Dur)   x  
Thiacetarsamide (Caparsolate)     Use with caution.
Thyroxine (Synthroid, Soloxine) x   Note: Hypothyroid dogs should not be bred.
Trimeprazine (Temaril-P)   x  
Trimethoprim & Sulfadiazine (Tribrissen)   x  

**CAUTION: Some Kaopectate includes bismuth salicylate as an ingredient. Dogs that may have an allergy to aspirin, or are taking aspirin, steroids, or another non-steroidal anti-inflammatory drug (NSAID) such as Rimadyl, EtoGesic, or Deramaxx should not be given the formulation with bismuth salicylate unless directed by a veterinarian.

Click here for a pdf version of this article.  See related products at Pet Supplies  
Print Article | Email Article
Drs. Foster & Smith Lawn Guard ®
Drs. Foster & Smith Lawn Guard ®
As low as $9.99
Drs. Foster & Smith Lawn Guard® Extra Strength Tablets
Drs. Foster & Smith Lawn Guard® Extra Strength Tablets
As low as $14.99
Doggie Dooley In-Ground Waste Digester Systems
Doggie Dooley In-Ground Waste Digester Systems
As low as $44.99
Drs. Foster & Smith Lawn Guard® Regular Strength Tablets
Drs. Foster & Smith Lawn Guard® Regular Strength Tablets
As low as $9.99

Facebook YouTube Blog Connect with us

Subscribe to email newsletters:
featuring helpful articles, tips and online only product specials from Drs. Foster & Smith. Learn more here !

About Us Article Reprints Awards & Memberships Request a FREE Catalog Tell a Friend
Meet Our Staff Terms & Use Site Map Free Newsletters Links to Us
Visit our other websites: Doctors Foster and Smith Pet Supplies - Quality Aquatic Life Direct to Your Door
For product information, call 1-800-826-7206

Copyright © 1997-2015, Petco Wellness, LLC. All rights reserved.
2253 Air Park Road, P.O. Box 100, Rhinelander, Wisconsin, 54501.
Terms of Use | Privacy Policy | Your CA Privacy Rights | Copyright Claims | Pet Medical Records Policy