Antihistamines and decongestants.
Diphenhydramine, (Benadryl, Sominex, Nytol, Sleep-Eze, various cough preparations), clemastine (Tavist), brompheniramine and chlorpheniramine (Chlor-Trimeton and various cough preparations), dimenhydrinate (Dramamine), meclizine (Bonine), cyclizine (Marezine), terfenadine (Seldane), hydroxyzine (Atarax, Vistaril), and loratidine (Claritin).
Histamines are released by body tissues during an allergic reaction and if injuries to certain cells during infections. Antihistamines block the attachment of histamine to cells and help to reduce the effects of histamine.
Varies depending upon the product.
Common signs may range from depression with respiratory problems to hyperexcitability with muscle tremors, seizures, and hyperactivity. Vomiting, dilated pupils, increased body temperature, disorientation, heart rhythm abnormalities, and increased or decreased heart rate may be seen.
Induce vomiting if patient is alert. Seek veterinary attention.
General treatment: The induction of vomiting may be continued, gastric lavage is performed, and activated charcoal is administered.
Supportive treatment: Medications are administered to control seizures and heart rhythm abnormalities. Hyperthermia, if present, is treated. IV fluids are administered. Antihistamines are excreted through the kidneys so good urine production is necessary.
Specific treatment: Unavailable.