Toxin
Thought to be due to an unknown compound in the "fleshy" part of the grape. There have been no problems associated with grape seed extract.

Source
Grapes and raisins.

General Information
Many dogs like raisins and grapes. They should only be given in a very limited amount on an infrequent basis, and should not be left where a dog or cat can have access to them. The unknown toxin damages the kidneys.

Toxic Dose
Exact toxic dose is unknown, but has been estimated as low as 1/3 ounce of grapes per pound of body weight, and 0.05 ounces of raisins per pound of body weight.

Signs
Vomiting, diarrhea, lack of appetite, lethargy, or abdominal pain.

Immediate Action
Induce vomiting and seek veterinary attention.

Veterinary Care
General treatment: The induction of vomiting may be continued, gastric lavage is performed, and activated charcoal administered, if needed.

Supportive treatment: The animal will be monitored and treated for kidney disease/failure with fluids, diet change, and medications.

Specific treatment: Unavailable.

Prognosis
Variable