Pet Education
Pet Education Pet Education Pet Education

Learn about Vetco
Free Shipping on orders over $49
Novobiocin (Albaplex®, Delta Albaplex®)
Veterinary & Aquatic Services Department, Drs. Foster & Smith
Print Article | Email Article
Bookmark and Share
Click here for a pdf version of this article. 


Novobiocin, an antibiotic, is an ingredient in several combination products used to treat dogs. Contact your veterinarian if your pet experiences vomiting, diarrhea, lack of appetite or a rash while being treated with novobiocin-containing medications.

Generic Name

Brand Names
Combination Products
Albaplex contains Novobiocin and Tetracycline
Delta Albaplex contains Novobiocin, Tetracycline, and Prednisolone

Type of Drug
Bacteriocidal antibiotic

Form and Storage
Store in tight containers at room temperature.

Indications for Use
Treatment of susceptible gram positive bacteria.

General Information
FDA approved for use in dogs. Available by prescription. The drug interferes with the ability of the bacteria to make protein, nucleic acid, and cell walls thereby killing the bacteria. Delta Albaplex has the maximum benefit if used in the first 48 hours of treatment, then Albaplex should be used for the rest of the treatment.

Usual Dose and Administration
Contact your veterinarian. Not used in cats. Duration of treatment depends on the reason for treatment and the response to treatment.

Side Effects
May see fever, vomiting, diarrhea, lack of appetite, rashes, and blood disorders. In humans, allergic reactions and liver disease have also been seen.

Do not use in patients who are hypersensitive (allergic) to it.

Not for use in patients with liver disease or blood disorders.

Not for use in pregnant or nursing animals.

Drug or Food Interactions
May decrease the elimination of other drugs by the liver and bile (such as penicillins and cephalosporins).

Because it contains a steroid, Delta Albaplex is not for use in animals with tuberculosis, Cushing's disease, or stomach ulcers and should be used with caution in patients with diabetes mellitus, kidney disease, congestive heart failure, high blood pressure, osteoporosis (loss of calcium in the bones), fungal diseases, or predisposition to inflammation of the blood vessels.

No known food interactions.

No information available.

Keep this and all other medications out of the reach of children and pets.

If you think your pet has been poisoned...

Contact your veterinarian or one of the Animal Poison Hotlines (listed below) if you think your pet may have accidentally received or been given an overdose of the medication.

**ASPCA Animal Poison Control Center - 24-hour service available throughout North America.

1-888-4ANI-HELP (1-888-426-4435). $65.00 per case, billed to caller's credit card.

Follow-up calls can be made for no additional charge by dialing 888-299-2973.

There is no charge when the call involves a product covered by the Animal Product Safety Service.

**Pet Poison Helpline - 24-hour service available throughout North America for pet owners and veterinary professionals who require assistance with treating a potentially poisoned pet.

1-800-213-6680 ($59.00 per incident). Staffed 24-hours a day.

Updated 6/20/17

Click here for a pdf version of this article. 
Print Article | Email Article